Santillan, 34-1 (18 KOs), began his career at junior welterweight in 2012 and has spent most of his career at welterweight. A 34-year-old from San Diego, Santillan fought Brian Norman Jnr for the vacant WBO welterweight title in his hometown in 2024, and was knocked out. He bounced back with wins in his two most recent fights, leading into his debut in a third weight class.
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